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It produces its psychoactive effects by promoting the release of the neurotransmitters serotonin, dopamine, and norepinephrine in the brain. Recreational MDMA use is popularly associated with dance parties, electronic dance music, and the club and rave scene.

Physical Effects

Stimulation – MDMA is popularly known for being stimulating and energetic. This encourages activities such as running, climbing, and dancing in a way that makes MDMA a popular choice for musical events such as festivals and raves.

Spontaneous bodily sensations – The “body high” of MDMA can be characterized as a moderate to extreme euphoric tingling sensation that encompasses the entire body. This sensation maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached.

Physical euphoria – Physical euphoria is a prominent aspect of the MDMA experience and occurs reliably when MDMA is used responsibly, and can lead to profound feelings of social and physical disinhibition.

Cognitive Effects

The general headspace of MDMA is described by many as one of pronounced mental stimulation, feelings of love, empathy, openness, and a pronounced sense of rejuvenation and euphoria.
It is capable of producing a large number of cognitive effects that are typically associated with entactogens and stimulants. The most prominent of these effects include:

Amnesia – Very high doses of MDMA can sometimes cause partial amnesia.
Anxiety suppression
Disinhibition
Empathy, affection, and sociability enhancement
Emotion enhancement
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Cognitive euphoria – Strong emotional euphoria and feelings of happiness are present in MDMA and are likely a direct result of a concerted mechanism of serotonin, norepinephrine, and dopamine release.

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Enhancements
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The effects which occur during the offset of an entactogen or stimulant experience generally feel negative and uncomfortable in comparison to the effects which occurred during its peak.
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